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PHILADELPHIA CHROMOSOME
Descriptors Found:
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DeCS
Descriptor
English
:
Philadelphia Chromosome
Descriptor
Spanish
:
Cromosoma Filadelfia
Descriptor
Portuguese
:
Cromossomo Filadélfia
Synonyms
English
:
Ph1 Chromosome
Tree Number:
A11.284.187.520.300.325.345.500
A11.284.187.520.300.505.515.500
C23.550.210.870.680
G05.360.162.520.300.325.345.700
G05.360.162.520.300.505.515.700
G05.365.590.175.870.680
Definition
English
:
An aberrant form of human
CHROMOSOME 22
characterized by translocation of the distal end of
chromosome 9
from 9q34, to the long arm of
chromosome 22
at 22q11. It is present in the
bone marrow cells
of 80 to 90 per cent of
patients
with chronic myelocytic
leukemia
(
LEUKEMIA
, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
See Related
English
:
Oncogene Proteins, Fusion
History Note
English
:
86; was see CHROMOSOMES, HUMAN, 21-22 1978-85
Allowable Qualifiers
English
:
DE
drug effects
RE
radiation effects
Record Number:
19631
Unique Identifier:
D010677
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS